Vaginal dryness, vaginal thinning, and what is called “atrophy” are very common problems for menopausal women. Estrogens are responsible for the thickened, elastic, lubricated tissue of the vagina and vulva. When estrogen levels decline, the vulva loses its collagen, fat, and water-retaining ability. As a result, it becomes flattened, thin, and dry and loses tone. […]
Author Archives: Dr. David K. Shefrin
Recommened Journal Articles: Cundy, T., et al. “Spinal bone density in women using depot medroxyprogesterone contraception.” Obstetrics and Gynecology, October 1998, 92 (4 pt 1): 569-73. Feldman, D. L., et al. “Cytoplasmic glucocorticoid binding proteins in bone cells.” Endocrinology, 1975, 96: 29-36. Gaby, Alan R. Preventing and Reversing Osteoporosis. Rocklin, Cal.: Prima Publications, 1995.
Recommened Journal Articles: Bilimoria, M. M., et al. “Estrogen replacement therapy and breast cancer: analysis of age of onset and tumor characteristics.” Annals of Surgical Oncology, 1999, 6: 200-7. Bluming, A.Z., et al. “Hormone replacement therapy in women with previously treated primary breast cancer.” Proceedings of the Annual Metting of the American Society of Clinical […]
Recommened Journal Articles: Bradlow, H. L., et al. “Indole-3-carbinol: A novel approach to breast cancer prevention.” Appearing in “Cancer Prevention. From the Laboratory to the Clinic: Implications of Genetic, Molecular and Preventive Research,” Annals of the New York Academy of Sciences, September 1995, 768: 180-200. And also: “Multifunctional aspects of the action of indole-3-carbinol as […]
Recommened Journal Articles: Cowan, L.D., “Breast cancer incidence in women with a history of progesterone deficiency” American Journal of Epidemiology, August 1981, 114:209-17. Dew, J.,”A cohort sudy of hormonal replacement therapy given to women previously treated for breast cancer.” Climacteric, 1998, 1:137-42. Fishman, J.,”Increased estrogen-16-alpha-hydroxylase activity in women with breast and endometrial cancer.” Journal of Steroidal Biochemistry, April […]
Couples considering having a baby can utilize a home ovulation test kit supplied from a pharmacy in order to pinpoint the best time to conceive a child. The most fertile time for a woman is usually the first two weeks before her menses begin. At this time, the pituitary gland begins increasing production of luteinizing […]
Recommened Journal Articles: Araneo, B., et al. “DHEAS as an effective vaccine adjuvant in elderly humans.” Annals of the New York Academy of Sciences, 1995, 774: 232-48. Arlt, W., et al. “Dehydroepiandrosterone replacement in women with adrenal insufficiency.” New England Journal of Medicine, September 30, 1999, 341 (14): 1013-20 Barrett-Connor, E., et al. “The epidemiology […]
Overview Dysfunctional uterine bleeding (DUB) refers to irregular or heavy menstrual bleeding that occurs in the absence of an anatomical abnormality such as a tumor, fibroid, or other lesion. The majority of cases of DUB are associated with anovulatory bleeding, which is menstruation that occurs in the absence of ovulation. DUB is the most common […]
Recommened Journal Articles: 1.) Estriol in the Management of the Menopause: by Tzingounis, Aksu, Greenblatt: JAMA 239:1638-1641, 1978. 2.) Effect of Estriol Administration on the Hypogonadal Woman: Schiff, Wentworth, Koos: Fertility and Sterility: Vol 30, No. 3, Sept 1978. 3.) The Agonistic and Antagonistic Actions of Estriol: Clark and Markaverich: J. Steroid Biochem, Vol. 20, […]
Recommened Journal Articles: Baker, Valerie L. “Alternatives to oral estrogen replacement: Transdermal patches, percutaneous gels, vaginal creams and rings, implants and other methods of delivery.” Obstetrics and Gynecology Clinics of North America, June 1994, 21(2): 271-97.